Projects

Research and scientific software projects by Dr Tahir Ali.

Research and software projects connecting genome variation, evolutionary processes, ecological change, biodiversity, and reproducible scientific computation.

Evolutionary and population genomics

How drift, selection, gene flow, demographic history, and environmental change shape genetic variation across time and space.

Visual summary of temporal population-genomic analyses
Current research

Temporal genomics

Temporal genomics detects evolutionary change directly by tracking allele-frequency shifts across generations. Repeated sampling of natural Arabidopsis lyrata populations, separated by approximately two decades, makes it possible to quantify recent genomic change and compare observed shifts with neutral expectations.

Genome-wide analyses examine how much change is consistent with drift, which loci exceed demographic expectations, and whether candidate regions show coherent relationships with environmental trends, functional annotation, or genomic constraint. The broader aim is to understand how standing genetic variation, demography, and selection jointly shape evolutionary responses to rapid environmental change.

Temporal dataGenetic driftSelectionGenomic constraintClimate change
Genomic analyses of hybridisation and introgression
Current research

Hybridisation genomics

Hybridisation generates new genetic combinations, can facilitate adaptation, and may contribute to the formation or collapse of species boundaries. This work investigates hybridisation in Arabis and related Brassicaceae by combining high-throughput sequencing, experimental crosses, field studies, and phenotyping.

Patterns of introgression, ancestry dynamics, segregation distortion, and the architecture of reproductive barriers are used to ask why some genomic regions cross species boundaries while others are retained or removed. Comparative work across experimental and natural hybrid systems provides insight into gene flow, adaptation, and diversification under changing environments.

IntrogressionGene flowReproductive barriersExperimental crosses
Plant climate adaptation and seed dormancy research
Published research

Climate adaptation and seed dormancy

This research examines plant responses to past and present climate change through phylogeography, landscape genetics, and adaptive seed dormancy. Molecular, ecological, and spatial analyses reveal how Quaternary climate oscillations, glacial refugia, recolonisation, and habitat fragmentation have shaped present-day diversity and species distributions.

Experimental studies in Arabidopsis thaliana investigate heat-induced secondary dormancy as an adaptive mechanism that adjusts germination timing to environmental conditions. Together, these lines of work connect historical range dynamics with contemporary trait evolution and help clarify how plants persist under environmental variability.

Local adaptationSeed dormancyLandscape geneticsClimate response
Phylogeographic patterns across Eurasia and North Africa
Published research

Phylogeography of Microthlaspi

Range-wide sampling and population-genetic analyses reconstruct the evolutionary history, migration, and genetic structure of Microthlaspi across Eurasia and North Africa. AFLP and sequence data show how climatic heterogeneity, selfing, and fragmented distributions have shaped genetic diversity.

The work revealed that M. erraticum extends from the Alps into Central Asia, while M. perfoliatum survived in multiple Pleistocene refugia and recolonised Europe through complex routes. Central Europe emerged as a contact zone among divergent lineages, illustrating how climate, geography, and historical demography combine to structure present-day biodiversity.

Range dynamicsHistorical demographyPleistocene refugiaMigration

Genome resources and biological interactions

Genome assembly, plant-associated communities, and pathogen evolution across host and environmental contexts.

Genome assembly and plant-microbe analysis workflow
Current research

High-resolution genomics of plant-microbe systems

This work develops high-quality, chromosome-level genome assemblies for Brassicaceae species and genomic resources for associated phyllosphere bacterial communities. PacBio HiFi, Oxford Nanopore, Hi-C, and Illumina data are integrated to resolve genome structure, gene content, and assembly quality in both host plants and key bacterial hub taxa.

The resulting resources support comparative genomics, functional-gene discovery, and investigations of plant-microbe interactions. They also provide a reliable genomic foundation for downstream population, evolutionary, and community analyses.

Genome assemblyPacBio HiFiOxford NanoporeHi-CPhyllosphere
Fungal diversity and plant-associated community research
Published research

Fungal diversity, systematics, and communities

Phylogenetic and morphological analyses clarify fungal diversity in forest and plant-associated systems. Taxonomic work on Cortinarius sect. Riederi and Inocybe subgenus Inocybe resolved overlooked lineages, complex synonymies, and previously unrecognised species.

Community-level research examines root endophytic fungi in non-mycorrhizal Microthlaspi. Large-scale sampling and multilocus data indicate that a small number of dominant fungal groups are widespread across Europe, with environmental gradients contributing more strongly to community structure than host genotype or simple geographic distance.

Fungal systematicsEndophytesCommunity ecologyEnvironmental filtering
Evolution and spread of downy mildew pathogens
Published research

Emergence and evolution of downy mildew pathogens

Field surveillance, molecular phylogenetics, and population genetics are used to study the emergence and spread of downy mildew pathogens affecting ornamental and crop plants in Europe. Work on Peronospora aquilegiicola documented its rapid movement from East Asia into Britain and Germany and evaluated the risk to cultivated and native Aquilegia.

Complementary studies of Pseudoperonospora cubensis and Plasmopara halstedii revealed changes in virulence, host range, lineage structure, and patterns consistent with multiple introductions or host-associated differentiation. These systems show how pathogen evolution, trade, host availability, and dispersal interact to create new agricultural and biodiversity risks.

Disease emergencePopulation structureHost rangePathogen surveillance

Systematics and biodiversity

Systematics and taxonomy of Microthlaspi and related Brassicaceae
Published research

Systematics of Microthlaspi and Coluteocarpeae

This project addresses longstanding taxonomic problems in the Brassicaceae tribe Coluteocarpeae, with particular emphasis on Microthlaspi and related genera. Nuclear and chloroplast phylogenies, combined with critical morphological study, clarified relationships among major lineages and supported revised generic boundaries.

The integrative approach revealed cryptic diversity, enabled the recognition and description of new taxa, and produced taxonomic treatments, distribution information, and diagnostic evidence for future research. It demonstrates why molecular data and careful morphological reassessment are most powerful when interpreted together.

PhylogeneticsTaxonomySpecies discoveryMorphology
Research record

Publications and professional experience

Peer-reviewed articles, preprints, manuscripts, teaching, and research roles spanning evolutionary genomics, plant adaptation, phylogeography, systematics, fungal biology, and pathogen evolution.

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